p120 inhibits LPS/TNFα-induced endothelial Ang2 synthesis and release in an NF-κB independent fashion.
Cytokine（2019）
Abstract
•p120 inhibits LPS/TNFα-induced endothelial Ang2 synthesis and release.•p120-mediated repression of Ang2 is in an NF-κB independent manner.•Transcription factor Ets1 mediates LPS/TNFα-induced Ang2 expression.•p120 inhibits LPS/TNFα-induced upregulation of Ets1.
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Key words
Endothelial cell,p120,Angiopoietin-2,NF-κB,Ets1
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