Structure-based Optimization of a PDZ-binding Motif Within a Viral Peptide Stimulates Neurite Outgrowth

Zakir Khan,Elouan Terrien,Florent Delhommel,Cynthia Lefebvre-Omar,Delphine Bohl,Sandrine Vitry, Clara Bernard,Juan Ramirez,Alain Chaffotte, Kevin Ricquier,Renaud Vincentelli,Henri Buc,Christophe Prehaud,Nicolas Wolff,Monique Lafon

Journal of Biological Chemistry（2019）

引用 14|浏览49

关键词

serine,threonine protein kinase,PDZ domain,neurite outgrowth,protein-protein interaction,viral protein,interfering peptide,neurodegenerative diseases,nuclear magnetic resonance,structure-function analysis,therapeutic drug candidate

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