Nesfatin-1 protects PC12 cells against high glucose-induced cytotoxicity via inhibiting oxidative Stress, autophagy and apoptosis.

Simin Nazarnezhad,Majid Rahmati,Asghar Shayannia,Zahra Abbasi,Majid Salehi,Mehdi Khaksari

NeuroToxicology（2019）

引用 19|浏览1

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摘要

•Nesfatin-1 reduces intracellular ROS in PC12 cells following glucose-induced neurotoxicity.•Nesfatin-1 reduces apoptosis of PC12 cells following glucose-induced neurotoxicity.•Nesfatin-1 reduces autophagy of PC12 cells following glucose-induced neurotoxicity.

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关键词

Nesfatin-1,High glucose neurotoxicity,Reactive oxygen species,Autophagy,Apoptosis

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