Maternal n-3 PUFAs deficiency during pregnancy inhibits neural progenitor cell proliferation in fetal rat cerebral cortex

International Journal of Developmental Neuroscience（2019）

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摘要

•Maternal dietary n-3 PUFAs deficiency inhibited NPCs proliferation in fetal rat cerebral cortex.•Decreased cortical NPCs proliferation did not originate from increased NPCs apoptosis.•Decreased NPCs proliferation might be mediated by selective down-regulation of cyclin E protein.

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AA,BrdU,CC,CDK2,CNS,CP,DAPI,DB-FFAP,Def.,DG,DHA,DPA,EPA,FAMEs,GC,GD,IZ,LA,LV,NPCs,PPARs,PUFAs,SVZ,VZ

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