Update of the DevTox data database for harmonized risk assessment and alternative methodologies in developmental toxicology: Report of the 9th Berlin Workshop on Developmental Toxicity

Roland Solecki,Martina Rauch,Andrea Gall,Jochen Buschmann,Rupert Kellner, Olena Kucheryavenko, Anne Schmitt, Nathalie Delrue,Weihua Li,Jingying Hu,Michio Fujiwara,Makiko Kuwagata,Alberto Mantovani,Susan L. Makris,Francisco Paumgartten,Gilbert Schönfelder,Steffen Schneider,Silvia Vogl,Nicole Kleinstreuer,Marlon Schneider

Reproductive Toxicology（2019）

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摘要

•Progress towards a harmonized human health risk assessment in developmental toxicology.•Future improvement of in-vitro methods for developmental and reproductive toxicology and potential relevance of alternative species in testing of developmental effects.•Development of animal-free test strategies and alternatives to animal testing.•Risk and hazard assessment of developmental and endocrine effects.

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关键词

DevTox update,Categorised anomalies,Developmental toxicology,Alternative methods,Harmonized terminology,Risk assessment

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