An Efficient One-Pot Four-Component Synthesis of 9-Aryl-hexahydroacridine-1,8-dione Derivatives in the Presence of a Molecular Sieves Supported Iron Catalyst
Catalysis letters(2019)
摘要
A series of 9-aryl-hexahydroacridine-1,8-diones are synthetized with good to excellent yields (50–99%) via a one-pot four-component reaction of dimedone, aromatic aldehydes and ammonium acetate in the presence of 4 Å molecular sieves modified with iron(III) as an efficient heterogeneous catalyst, in ethanol. The process offers the advantages of high yields, mild reaction conditions and easy work-up procedure. The catalyst can be reused without significant loss of activity.
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关键词
Heterogeneous catalysis,Multicomponent reactions,9-Aryl-hexahydro-acridine-1,8-dione,Iron,4 Å Molecular sieves
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