Benzoxaboroles as dynamic covalent receptors for bioconjugation and transport of nucleosides and related drugs: Proof of action in HeLa cells.
Bioorganic Chemistry(2019)
摘要
•Evidence of binding between benzoxaborole and pharmacological agents.•Novel spectroscopic approach to study benzoxaborole and analyte binding.•Significant differences in the cytotoxicity of the Benzoxaborole-drug conjugates.•Near-infrared emissive boronolectin for conjugation and tracking.
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关键词
Boronolectin,Chemotherapeutic,Bioconjugation,Fluorescence,Cyanines,HeLa cells
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