Benzoxaboroles as dynamic covalent receptors for bioconjugation and transport of nucleosides and related drugs: Proof of action in HeLa cells.

Bioorganic Chemistry(2019)

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摘要
•Evidence of binding between benzoxaborole and pharmacological agents.•Novel spectroscopic approach to study benzoxaborole and analyte binding.•Significant differences in the cytotoxicity of the Benzoxaborole-drug conjugates.•Near-infrared emissive boronolectin for conjugation and tracking.
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关键词
Boronolectin,Chemotherapeutic,Bioconjugation,Fluorescence,Cyanines,HeLa cells
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