Proliferation and osteogenic differentiation of human mesenchymal stem cells in PCL/silanated silica composite scaffolds for bone tissue regeneration

This illustration is representative of the physical and biological characteristics of the composite scaffold. The composite scaffold, which has been fabricated through three processes, exhibits excellent improved physical properties as well as outstanding osteogenic differentiation. Silanated silica reinforced composite scaffold showed good performance including tensile modulus, water absorption ability, cell initial attachment, proliferation and osteogenic differentiation and have the potential to become implantable materials in hard bone tissue regeneration.