T12. Freezing is Associated With Higher Amygdala Metabolism in Female Adolescent Monkeys

Biological Psychiatry(2019)

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Abstract
Although freezing to potential threats is an evolutionarily conserved defense mechanism across species, excessive freezing during adolescence is a risk factor for psychiatric disorders like anxiety and depression. Neuroimaging studies on this risk have implicated a network of regions including the central nucleus of the amygdala (Ce). Here, we extend these previous studies, by utilizing the unique opportunity provided by the California National Primate Research Center to study animals that have been reared in large, outdoor, naturalistic social groups.
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Key words
Neuroimaging,Rhesus Monkey,Anxiety,18FDG PET
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