Number of infections suffered by a focal individual in a two‐strain SIS model with partial cross‐immunity

MATHEMATICAL METHODS IN THE APPLIED SCIENCES(2019)

引用 6|浏览1
暂无评分
摘要
We study a stochastic model for the spread of two pathogen strains-termed type 1 and type 2-among a homogeneously mixing community consisting of a finite number of individuals. In the model, we assume partial cross-immunity, exogenous streams of infection, and that the degree of severity of a newly infective individual depends on who this infective individual was infected by. The aim is to characterize the joint probability distribution of the numbers M-1 and M-2 of type-1 and type-2 infections suffered by a focal individual during an outbreak of the disease. We present iterative procedures for computing the probability mass function of (M-1,M-2) under the assumption that the initial state of the focal individual is known, and a numerical study of the model is performed to investigate the influence of certain key parameters on the spread of resistant bacteria in hospitals.
更多
查看译文
关键词
computational methods in Markov chains,continuous-time Markov chains on discrete state spaces,epidemiology
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要