Loading zedoary oil into pH-sensitive chitosan grafted mesoporous silica nanoparticles via gate-penetration by supercritical CO2 (GPS)

Jingfu Jia,Xiaojing Liu, Kongyun Wu,Xue Zhou,Fahuan Ge

Journal of CO2 Utilization（2019）

引用 10|浏览3

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摘要

•Drug was loaded in gated porous nanoparticles directly by supercritical CO2.•Drug release of prepared ZO@CS-MSN was pH-sensitive.•GPS was of high drug-loading efficacy and no structure damage.•Water-insoluble essential oil was used as target drug.

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关键词

CO2,Drug loading,Gate-penetration,Stimuli-responsive,Zedoary oil

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