Supercritical carbon dioxide assisted impregnation of eugenol into polyamide fibers for application as a dental floss

•Eugenol was incorporated into polyamide fibers by scCO2-assisted impregnation.•Pressure and depressurization rate influenced eugenol loading.•Eugenol release in artificial saliva is suitable for application as dental floss.•The impregnated material maintained its mechanical properties.•Eugenol-loaded dental floss presented strong in vitro antimicrobial activity.