Autism spectrum disorder and neurodevelopmental delays in children with giant omphalocele.
Journal of Pediatric Surgery(2019)
Abstract
There is a significant rate of ASD in GO survivors. Neurodevelopmental delays, language delays, and genetic abnormalities were strongly associated with ASD. Neurological impairments were present in nearly half of GO children. Surrogate markers of disease severity were associated with below average neurodevelopmental scores. Level of evidence Level IV.
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Key words
Giant omphalocele,Autism spectrum disorder,Autism diagnostic observation schedule,Neurodevelopmental delay,Pulmonary hypoplasia,Pulmonary hypertension
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