Muscle Resting and TGF-β Inhibitor Treatment Prevent Fatty Infiltration Following Skeletal Muscle Injury.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology(2019)
摘要
In addition to the potential clinical relevance of decorin treatment in situations involving muscle plasticity and regeneration, this study also demonstrates that a period of muscle resting is necessary following muscle injury to achieve efficient muscle regeneration which is associated with a reduction in fatty infiltration. Unreasonably early resumption of exercise brings no gain to regeneration, further highlighting that this resting period is necessary.
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关键词
Exercise,Fibro-adipogenic progenitors (FAPs),Hindlimb unloading,Intermuscular adipose tissue (IMAT),Muscle regeneration
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