The role of Wnt7B in the mediation of dentinogenesis via the ERK1/2 pathway.
Archives of Oral Biology(2019)
Abstract
•Wnt7b expressed in odontoblast layer of mouse tooth germ.•Wnt7b enhances dentin formation in Dmp1-cre;ROSA26Wnt7bf/f transgenic mice.•Wnt7b promotes proliferation and odontoblastic differentiation of MDPCs and A11.•Wnt7b mediates dentinogenesis partly via ERK1/2 pathway.
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Key words
Wnt7b,Dentinogenesis,MDPCs,ERK1/2
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