Tp47 induces cell death involving autophagy and mTOR in human microglial HMO6 cells
International Immunopharmacology(2019)
摘要
•There is a large amount of Tp47 in the cerebrospinal fluid of patients with neurosyphilis.•Tp47 induces autophagy and cell death in immunocytes of central nervous cells.•Tp47-induced cell death is involved in autophagy (autophagic death).
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关键词
Microglia,Tp47,Autophagy
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