Phase-contrast computed tomography: A correlation study between portal pressure and three dimensional microvasculature of ex vivo liver samples from carbon tetrachloride-induced liver fibrosis in rats.
Microvascular Research(2019)
Abstract
•PCCT technique demonstrates outstanding potential for 3D visualization of microvasculature in liver fibrosis.•Microvascular changes exhibited good correlations with the fibrosis area and portal pressure in the development of fibrosis.•Microvascular changes may serve as a new surrogate histopathological marker in prognosing portal hypertension.
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Key words
X-ray phase-contrast computed tomography,Portal hypertension,Liver fibrosis,Microvascular characterization,Three dimensional visualization
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