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MicroRNA expression profiles of neuron-derived extracellular vesicles in plasma from patients with amyotrophic lateral sclerosis.

Masataka Katsu,Yuka Hama,Jun Utsumi,Ken Takashina, Hiroshi Yasumatsu,Fumiaki Mori,Koichi Wakabayashi,Mikio Shoji,Hidenao Sasaki

Neuroscience Letters（2019）

Cited 55|Views16
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Abstract
•We extracted neuron-derived extracellular vesicles (EVs) in plasma from patients with ALS.•MicroRNA expression profiles of neuron-derived EVs were analyzed.•A total of 30 differentially-regulated miRNAs were identified in ALS.•MicroRNAs in neuron-derived EVs hold promise as potential biomarkers in ALS.
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Key words
Bioinformatics,MicroRNA,ALS,Extracellular vesicles
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