Plumbagin ameliorates liver fibrosis via a ROS-mediated NF-кB signaling pathway in vitro and in vivo

The mechanism of Plumbagin ameliorates liver fibrosis via a ROS-mediated NF-кB signaling pathway. The oxidative stress and the NF-κB signaling pathway are involved in the process of CCl4-induced rat liver fibrosis and that IL-1β-induces HSCs and PL effectively suppresses liver fibrosis via a ROS-mediated NF-кB signaling pathway.