Genetic Analysis and Evolutionary Changes of Porcine Circovirus 2.

Molecular Phylogenetics and Evolution(2019)

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摘要
•The origin and evolution of PCV2 were investigated based on a wide dataset of globally distributed sequences.•PCV2 genotypes displayed different codon usage patterns.•PCV2 is especially adapted to Sus scrofa, which contributed in shaping the PCV2 genome.•Several cross-species transmission events could be identified along circovirus history.
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关键词
PCV2,ORF2,Phylogenetic analysis,Codon usage,Specific-species adaptation
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