Toward personalized dose-prescription in locally advanced non-small cell lung cancer: Validation of published normal tissue complication probability models

Radiotherapy and Oncology(2019)

引用 27|浏览13
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摘要
•One AE2 and one RP2 model explained outcomes after RT in the investigated LA-NSCLC cohort.•Reduce AE2: lower mean esophageal dose particularly when giving concurrent chemo-RT.•Reduce RP2: lower mean lung dose particularly for old patients with pulmonary comorbidity.•Model performance was modest, encouraging incorporation of unaccounted for information.
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关键词
Radiotherapy,Lung cancer,Toxicity,Dose response,Esophagitis,Pneumonitis
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