Stable level of HIV transmitted drug resistance in Estonia despite significant scale-up of antiretroviral therapy

Pilleriin Soodla,Kristi Huik,Merit Pauskar,Lize Cuypers,Kristel Van Laethem,Heli Rajasaar,Eveli Kallas, Helen Lepa, Anna Velts-Lindh,Ene-Ly Jõgeda,Irja Lutsar,Radko Avi

Infection, Genetics and Evolution（2019）

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摘要

•Estonia's HIV epidemic is mainly comprised of CRF06_cpx viruses.•Fylgenetic clustering is low at 11%.•TDR remained stable at a moderate level in Estonia despite significant scale-up of antiretroviral therapy.•K103N is the main SDRM.•Only one SDRM transmission-pair was detected.

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关键词

Eastern Europe HIV epidemic,PWID,HIV-transmitted drug resistance,HIV in imprisoned subjects,HIV epidemiology

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