A new hepatoma cell line exhibiting high susceptibility to hepatitis B virus infection.

Youki Ueda,Weilin Gu,Hiromichi Dansako,Hironori Nishitsuji,Shinya Satoh,Kunitada Shimotohno,Nobuyuki Kato

Biochemical and Biophysical Research Communications（2019）

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摘要

Hepatitis B virus (HBV) infection, which increases the risk of cirrhosis and hepatocellular carcinoma and requires lifelong treatment, has become a major global health problem. However, host factors essential to the HBV life cycle are still unclear, and the development of new drugs is needed.

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关键词

Hepatitis B virus,Li23/NTCP,Subcloning,NTCP glycosylation,STING,Plural assay systems

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