Ca 2+ and CACNA1H mediate targeted suppression of breast cancer brain metastasis by AM RF EMF.
EBioMedicine(2019)
Abstract
We demonstrate that BCF, as a single agent or in combination with radiation, is a novel treatment approach to the treatment of brain metastases. This paradigm shifting modality warrants further clinical trials for this unmet medical need.
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Key words
Breast Cancer,Brain metastasis,Electromagnetic field,Radiofrequency,Calcium,Novel therapeutics,Cav3.2 T-type channel,Exosomes,Radiation,miRNA,Angiogenesis
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