Long-term outcomes after valve-sparing anatomical aortic root reconstruction in acute dissection involving the root.

Vadim Irimie, Alaa Atieh, Gjoko Kucinoski, Atanas Jankulovski,Michael Zacher,Paul P Urbanski

The Journal of Thoracic and Cardiovascular Surgery(2020)

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摘要
Objectives: To evaluate long-term results after valve-sparing surgery of acutely dissected aortic root in which a restoration of root anatomy adjusted to the existing aortic annulus diameter, rather than any kind of downsizing, was performed. Methods: Among 286 consecutive patients operated on because of type A aortic dissection during the last 17 years were 100 patients (35.0%), mean age 63 +/- 13 years (range, 29-88 years), in whom an anatomical restoration of the involved root was performed. Twenty-eight patients presented with severe (3+ or 4+), 37 with mild to moderate (2+), and 24 with mild (1+) insufficiency. In 5 patients, the valve was bicuspid. In all patients, a curative root repair with replacement of all dissected aortic wall was performed, containing a selective replacement of pathologic/dissected aortic sinuses, which were 1, 2, or all 3 sinuses in 62, 32, and 6 patients, respectively. Concomitant cusp repair was necessary in 18 patients. Results: Thirty-day mortality was 1.0%. Survival was estimated starting with surgery and was 89.4 +/- 3.4% (95% confidence interval, 80.5-94.4) and 68.8 +/- 6.4% (95% confidence interval, 54.4-79.5) at 5 and 12 years, respectively. No patient required reoperation on the aortic root and/or valve during the followup period of 70 +/- 50 (range, 3-202) months. A freedom from any aortic valve/root reintervention and/or relevant (>2+) aortic insufficiency at 12 years was 100%. Conclusions: Selective replacement of pathologic sinuses offers an anatomophysiological albeit curative restoration of acutely dissected aortic root resulting in excellent and durable outcomes in selected patients with acute aortic dissection.
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关键词
aortic dissection,aortic root,aortic valve,valve-sparing root repair,selective sinus replacement
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