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High-intensity aerobic training lowers blood pressure and modulates the renal renin-angiotensin system in spontaneously hypertensive rats

Jeeser Alves Almeida,Daisy Motta-Santos,Bernardo Assis Petriz,Clarissa Pedrosa Da Costa Gomes,Murilo Esteves Nogueira,Rinaldo Wellerson Pereira,Ronaldo Carvalho Araujo,Jonato Prestes,Octavio Luiz Franco

CLINICAL AND EXPERIMENTAL HYPERTENSION（2020）

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Abstract
Background: This study aimed to verify the effects of high-intensity aerobic training (HIAT) on BP control and renin-angiotensin system (RAS) components in renal tissue of SHR. Ten SHRs received HIAT or control for 8-weeks. At the end of the training, the SBP showed a reduction of similar to 30mmHg (p < .01) in HIAT and increased by similar to 15 mmHg in the control group. HIAT resulted in a higher release of nitrite, IL-6, ACE2 and ATR2. These results indicated an association between BP, NO and renal RAS.
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Key words
Renin-angiotensin system,high-intensity exercise,blood pressure,hypertension
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