Anticonvulsant and anti-apoptosis effects of salvianolic acid B on pentylenetetrazole-kindled rats via AKT/CREB/BDNF signaling.

Xiaoxiang Yu,Qiaobing Guan,Yanping Wang,Heping Shen,Liping Zhai,Xudong Lu,Yuhua Jin

Epilepsy Research（2019）

引用 38|浏览6

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摘要

•Sal B treatment has neuroprotective and antiepileptic effects against a PTZ-induced seizure rat model.•The effects of Sal B may be attributed to inhibition of neuronal apoptosis.•Our findings provide a novel intervention strategy for human epilepsy.

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关键词

Salvianolic acid B,Neuronal apoptosis,Epilepsy,AKT/CREB/BDNF signaling

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