Intermittent abortive reactivation of Epstein-Barr virus during the progression of nasopharyngeal cancer as indicated by elevated antibody levels.

Xiaoyi Guo,Tingdong Li,Fugui Li, Yarui Xu,Han Wang,Weimin Cheng,Jiabao Tang,Guoliang Zhou,Honglin Chen,Munhon Ng,Mingfang Ji,Shengxiang Ge,Ningshao Xia

Oral Oncology（2019）

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摘要

•Systematic analysis of antibodies specific to different life cycle EBV antigens.•99 (36.3%) early stage (stage I&II) NPC cases for analysis.•Correlation between antibody level and progression of NPC, especially tumour size.•Intermittent abortive reactivation of EBV during the progression of NPC.

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关键词

Epstein-Barr virus,Nasopharyngeal carcinoma,Antibody profile,Tumour progression,Stage

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