Multirecombinant Enterovirus A71 Subgenogroup C1 Isolates Associated with Neurologic Disease, France, 2016-2017.

Stéphanie Tomba Ngangas,Alexander Lukashev,Gwendoline Jugie,Olga Ivanova,Jean-Michel Mansuy,Catherine Mengelle,Jacques Izopet,Anne-Sophie L'honneur,Flore Rozenberg, David Leyssene, Denise Hecquet,Stéphanie Marque-Juillet,David Boutolleau,Sonia Burrel,Hélène Peigue-Lafeuille,Christine Archimbaud,Kimberley Benschop,Cécile Henquell,Audrey Mirand,Jean-Luc Bailly

EMERGING INFECTIOUS DISEASES（2019）

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摘要

In 2016, an upsurge of neurologic disease associated with infection with multirecombinant enterovirus A71 subgeno-group C1 lineage viruses was reported in France. These viruses emerged in the 2000s; 1 recombinant is widespread. This virus lineage has the potential to be associated with a long-term risk for severe disease among children.

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关键词

3Dpol,5′ UTR,C1 subgenogroup,C1v2015 lineage,EV-A71,France,children,coxsackievirus,enterovirus,enterovirus infection,epidemiologic monitoring,genetic recombination,genomic region P1,most recent common ancestor,neurologic disease,neurologic manifestations,viruses,whole-genome sequencing

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