Impaired social discrimination behavior despite normal social approach by kallikrein-related peptidase 8 knockout mouse.

Hitomi Nakazawa,Yuka Suzuki,Yasuyuki Ishikawa,Yoshio Bando,Shigetaka Yoshida,Sadao Shiosaka

Neurobiology of Learning and Memory（2019）

引用 6|浏览12

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摘要

•Territory invasion up-regulated KLK8 enzyme activity and ErbB4 phosphorylation in the mouse hippocampus.•Klk8 knockout mice had impaired social discrimination.•Intraventricular injection of NRG1177-246 reversed social discrimination impairment of Klk8 knockout mice.

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关键词

Hippocampus,Social discrimination,Social memory,KLK8,NRG1-ErbB signaling

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