Safety evaluation of nivolumab added concurrently to radiotherapy in a standard first line chemo-radiotherapy regimen in stage III non-small cell lung cancer—The ETOP NICOLAS trial
Lung Cancer(2019)
摘要
•Immune- plus chemo-radiotherapy as promising strategy in curative setting of NSCLC.•Concurrent PD-1/L1-inhibition and radiotherapy not yet assessed in clinical trials.•Safety results of prospective trial of concurrent nivolumab and chemo-radiotherapy.•No unexpected adverse events or increased risk for severe pneumonitis observed.
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关键词
Non-small cell lung cancer,NSCLC,Chemotherapy,Radiotherapy,Cancer immunotherapy,Immune checkpoint inhibitors,PD-1 inhibitor,Nivolumab,Combination treatment
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