PO-01-033 A prospective study in 135 patients to evaluate the influence of transrectal and transperineal prostate biopsies in erectile function

The aim of this study is to evaluate prospectively the effect of TRUS and TPM-biopsies on erectile function, and to establish a comparison between them in this respect. All men who underwent transrectal or transperineal prostate biopsy completed an International Index of Erectile Function (IIEF-5) questionnaire before the procedure and on the 3rd and 6th month after. Transrectal and transperineal prostatic biopsies are performed following the standard procedure on both techniques. Statistical analyses used were a general descriptive analysis (continuous variables using a T test, and categorical data using chi-square analysis), a paired T test to compare each patient’s baseline score to their own follow up scores and a Pearson correlation coefficient to compare the number of cylinders and the difference between IEEF-5 prebiopsy and after 3 and 6 months. The questionnaire was completed by 198 patients. After the procedure, 135 (90 transrectal and 45 transperineal) subjects were re-evaluated at 3 and 6 months. The average age was 63.5. Prior to biopsy, 107 (82%) has ED: 4 (3%) severe, 49 (36%) moderate, 54 (40%) mild, and 28 patients (21%) had no ED, with a mean of IIEF 5 punctuation of 17,7. After 3 months the percentages were 3, 27.4, 38 and 29% respectively, and after 6 months 6, 28, 34 and 30% (IIEF means 17,95 and 17,77 respectively). We couldn’t find differences between the pre-biopsy IIEF-5 score and the post-biopsy 3 and 6-month IIEF-5 scores in the entire sample or even analysing transrectal or transperineal separately. No statistical differences were found either when we compared the number of cylinders with the difference between IEEF-5 prebiopsy and after 3 and 6 months.