Sleep in Mowat-Wilson Syndrome: a clinical and video-polysomnographic study

Veronica Di Pisa,Federica Provini,Sara Ubertiello,Silvia Bonetti,Emilia Ricci,Ivan Ivanovski,Stefano Giuseppe Caraffi,Lucio Giordano,Patrizia Accorsi,Salvatore Savasta,Federico Raviglione,Antonella Boni,Daniele Grioni,Claudio Graziano,Livia Garavelli,Duccio Maria Cordelli

Sleep Medicine（2019）

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摘要

•This is the first study of sleep in MWS using questionnaire and video-polysomnography (VPSG).•SDSC questionnaire revealed disturbances at the sleep–wake transition and in initiating and maintaining sleep.•VPSG documented reduction of total sleep time and increase of wake time after sleep.•Slowing of EEG background and a poverty of sleep figures were observed in all patients.•After age seven, sleep-related sub-continuous EEG epileptiform activity was observed.

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关键词

Mowat-wilson syndrome,Video-polysomnography,ESES,Sleep disturbances

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