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Postmortem brain tissue as an underutilized resource to study the molecular pathology of neuropsychiatric disorders across different ethnic populations

Eric Vornholt, Dan Luo,Wenying Qiu,Gowon O. McMichael,Yangyang Liu,Nathan Gillespie,Chao Ma,Vladimir I. Vladimirov

Neuroscience & Biobehavioral Reviews（2019）

Cited 11|Views14
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Abstract
•Gene expression serves as a functional intermediate between genotype and phenotype.•The etiologically relevant tissue for studying neuropsychiatric disorders is brain.•Most current postmortem brain banks lack in ethnic diversity and sample sizes.
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Key words
Postmortem brain,eQTL,GWAS,Neuropsychiatric disorders,Gene expression,Ethnic diversity
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