Postmortem brain tissue as an underutilized resource to study the molecular pathology of neuropsychiatric disorders across different ethnic populations
Neuroscience & Biobehavioral Reviews(2019)
Abstract
•Gene expression serves as a functional intermediate between genotype and phenotype.•The etiologically relevant tissue for studying neuropsychiatric disorders is brain.•Most current postmortem brain banks lack in ethnic diversity and sample sizes.
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Key words
Postmortem brain,eQTL,GWAS,Neuropsychiatric disorders,Gene expression,Ethnic diversity
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