PD66-01 PROXIMITY TO OIL REFINERIES AND RISK OF BLADDER CANCER: A POPULATION-BASED ANALYSIS

You have accessJournal of UrologyBladder Cancer: Epidemiology & Evaluation II (PD66)1 Apr 2019PD66-01 PROXIMITY TO OIL REFINERIES AND RISK OF BLADDER CANCER: A POPULATION-BASED ANALYSIS Mohamed Ray-Zack*, Preston Kerr, Yong Shan, Jacques Baillargeon, Yong-Fang Kuo, Hemalkumar Mehta, and Stephen Williams Mohamed Ray-Zack*Mohamed Ray-Zack* More articles by this author , Preston KerrPreston Kerr More articles by this author , Yong ShanYong Shan More articles by this author , Jacques BaillargeonJacques Baillargeon More articles by this author , Yong-Fang KuoYong-Fang Kuo More articles by this author , Hemalkumar MehtaHemalkumar Mehta More articles by this author , and Stephen WilliamsStephen Williams More articles by this author View All Author Informationhttps://doi.org/10.1097/01.JU.0000557463.70796.dfAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVES: Exposure to benzene and aromatic amines are risk factors for bladder cancer.Incidence rates according to proximity to oil refineries are largely unknown. We sought to determine proximity of oil refineries and bladder cancer incidence in the State of Texas, which is home to the largest number of oil refineries in the United States. METHODS: We used the Texas Cancer Registry database to identify patients diagnosed with bladder cancer from January 1, 2001 to December 31, 2014. The U.S. census data from 2010 was used to ascertain overall population size, age and sex distributions. Heat maps of the 28 active oil refineries in Texas were developed. Incidence of bladder cancer were compared according to proximity (<10 vs. ≥10 miles) to an oil refinery. Risk ratios (RR) were adjusted using a Poisson regression model. RESULTS: Results: A total of 45,517 incident bladder cancer cases were identified, of which 5,501 cases were within 10 miles of an oil refinery. In adjusted analyses, bladder cancer risk was significantly greater among males vs. females (RR 3.41, 95% Confidence Interval (CI), 3.33-3.50), and greater among people living within 10 miles from an oil refinery than those living outside a 10-mile radius from an oil refinery (RR 1.19, 95% CI, 1.08-1.31). A heat map demonstrates the locations of oil refineries and the varying incidences of bladder cancer at Texas ZIP codes (Figure 1). CONCLUSIONS: People living within 10 miles from oil refineries were at greater risk for bladder cancer. Further research into exposure to oil refineries and bladder cancer incidence is warranted. Source of Funding: This study was conducted with the support of a Department of Defense Peer Reviewed Cancer Research Program (PRCRP) Career Development Award (W81XWH1710576) and the Herzog Foundation (SBW). This study was supported by a Center for Translational Science Award by the NIH (TL1TR001440 and UL1TR001439) (MDR). Galveston, TX© 2019 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 201Issue Supplement 4April 2019Page: e1192-e1192 Advertisement Copyright & Permissions© 2019 by American Urological Association Education and Research, Inc.MetricsAuthor Information Mohamed Ray-Zack* More articles by this author Preston Kerr More articles by this author Yong Shan More articles by this author Jacques Baillargeon More articles by this author Yong-Fang Kuo More articles by this author Hemalkumar Mehta More articles by this author Stephen Williams More articles by this author Expand All Advertisement PDF downloadLoading ...