Dense CO2 technology: Overview of recent applications for drug processing/formulation/delivery

Chemical Engineering and Processing - Process Intensification(2019)

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摘要
•Different formulation strategies for drug delivery using dense CO2 are discussed.•Dense CO2-based processes for drug formulation development are reviewed.•Drug micronization, coprecipitation, encapsulation and coating are critically compared.•Examples of drug formulations recently developed are presented.
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关键词
Drug processing,Formulation development,Drug delivery,Dense CO2,Supercritical fluids
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