The place of heparins in the treatment of venous thromboembolism

Venous thromboembolism, in the form of lower limb deep vein thrombosis and its most dangerous complication that is a pulmonary embolism, is a common disease with an increasing incidence associated with the ageing population. The scheme of VTE treatment underwent changes when a new drug group — directly and selectively acting oral anticoagulants — was introduced. However, the scope of VTE therapy with parenterally administered low-molecular-weight heparins was wide, i.e., they produced vast progress in the disease’s treatment in the 1980s.