Temporal effects of laparoscopic sleeve gastrectomy on adipokines, inflammation, and oxidative stress in patients with impaired glucose homeostasis

•This study demonstrated that laparoscopic sleeve gastrectomy is associated with a reduction in adipokines and pro-inflammatory cytokines in the setting of obesity-related glucose dysregulation.•The study demonstrates that laparoscopic sleeve gastrectomy is associated with a reduction in plasma oxidative stress.•There is a close association between markers of glucose regulation with changes in leptin and markers of inflammation.