Isolation And Evaluation Of Antioxidant And Antibacterial Activity Of Flavonoid From Ficus Variegata Blume

INDONESIAN JOURNAL OF CHEMISTRY(2019)

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Abstract
Ficus variegata Blume is a specific plant of East Kalimantan. Flavonoid compound of F. variegata Blume was isolated by vacuum liquid and column chromatography, with previously extracted by maceration method using n-hexane and methanol, and fractionation using ethyl acetate solvent. The eluent used in isolation were n-hexane:ethyl acetate (8:2). Based on the results of elucidation structure using spectroscopy methods (GC-MS, NMR, and FTIR), 5-hydroxy-2-(4-methoxy-phenyl)-8,8-dimethyl-8H-pyrano[2,3-f] chromen-4-one was obtained. This compound has antibacterial and antioxidant activity.
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Key words
Ficus variegata Blume, flavonoid, antibacterial activities, antioxidant activity
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