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Synthesis of 4,5,6,7-tetrahydrobenzoxazol-2-ones by a highly regioselective Diels-Alder cycloaddition of exo-oxazolidin-2-one dienes with chalcones

Salvador Mastachi-Loza,Tania I. Ramírez-Candelero, Asenet Tapia-Bustamante,Carlos González-Romero,Eduardo Díaz-Torres,Joaquín Tamariz,Rubén A. Toscano,Aydeé Fuentes-Benítes

Tetrahedron Letters（2019）

Cited 3|Views14
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Abstract
•Synthesis of novel 4,5,6,7-tetrahydrobenzoxazol-2-ones.•Highly regioselective Diels-Alder cycloaddition.•The endo/exo stereoselectivity of synthetized compounds was dependent on the solvent, polarity and substituents.
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Diels-Alder reaction,Chalcone,Cyclization,Tetrahydrobenzoxazol-2-one,Benzoxazolone
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