Cycloartane Triterpenoids with Anti-melanin Deposition Activity

NATURAL PRODUCT COMMUNICATIONS(2018)

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Abstract
Bioactivity guided separation of the extract of Malaysian Garcinia sp. resulted in the isolation of 23-acetoxy-mangiferonic acid (1) and the absolute configuration of C-23 was elucidated to be R by the advanced Mosher's method. The anti-melanin deposition activity of 1 was caused by the down regulation of tyrosinase gene expression.
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Key words
Garcinia,Triterpenoids,Cycloartane,23-Acetoxy-mangiferonic acid,Anti-melanin deposition activity
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