A New Oxoaporphine Alkaloid from the Root of Dasymaschalon glaucum

Weerachai Silprakob, Nuntaporn Sukhamsri,Chutima Kuhakarn,Sakchai Hongthong,Surawat Jariyawat,Kanoknetr Suksen,Radeekorn Akkarawongsapat,Jitra Limthongkul,Narong Nantasaen,Vichai Reutrakul

NATURAL PRODUCT COMMUNICATIONS（2018）

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摘要

The first phytochemical investigation of the root of Dasymaschalon glaucum led to the isolation of a new oxoaporphine alkaloid 1 together with seven known compounds, duguevalline (2), stigmalactam (3), enterocarpam III (4), desmosdumotin B (5), spiraeamide (6), kaempferol-3-O-glucopyranoside (7) and beta-sitosterol (8). The chemical structures of all isolated compounds were established on the basis of their spectroscopic data. The cytotoxic and anti -HIV 1 RT activities of isolated compounds were also evaluated.

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关键词

Dasymaschalon glaucum,Annonaceae,Oxoaporphine,Aristolactam,Cytotoxic,Anti-HIV

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