A New Antibacterial Polyketide from the Endophytic Fungi Aspergillus fumigatiaffinis

Antonius R. B. Ola, Bibiana D Tawo,Henderiana L. L Belli,Peter Proksch, Dhana Tommy,Euis Holisotan Hakim

NATURAL PRODUCT COMMUNICATIONS（2018）

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摘要

A new antibacterial polyketide (-) palitantin was isolated from Aspergillus fumigatiaffnis, an endophytic fungi from a medicinal plant Tribulus terestris. The structure of the antibacterial metabolite was established using ID and 2D NMR together with mass spectroscopy. (-) Palitantin was found to inhibit the growth of Enterococcus faecalis UW 2689 and Streptococcus pneumoniae with MIC value of 64 mu g/mL.

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关键词

Tribulus terestris,Palitantin,Endophytic fungus,Antibiotic

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