RETRACTED:Effect of Dexmedetomidine on Comfort and Satisfaction of Patients

Purpose: the effect of ultrasonic-guided thoracic paravertebral block (TPVB) combined dexmedetomidine with ropivacaine on anesthesia and postoperative analgesia in patients undergoing thoracotomy is discussed in the Paper. Method: 60 patients undergoing thoracotomy (from January 2016 to June 2018)are selected from the Hospital and divided into groups (30 patients for experimental group and control group respectively) after EXCEL2007 is used to generate random numbers, of which dexmedetomidine and ropivacaine are infused before anesthesia induction for implementing TPVB in experimental group, and ropivacaine is infused before anesthesia induction for implementing TPVB in contract group. Thoracotomy is implemented under general anesthesia for the two groups to compare hemodynamics, anesthesia indicators, postoperative VAS score and cortisol level during operation. The results show that the difference of MAP, HR and BIS values in the two groups has no statistical significance at T0 and T1 (P>0.05); the MAP, HR and BIS values in experimental group are significantly higher than that in control group at T3 and T4 (P<0.05); VAS scores of patients in experimental group are obviously lower than that in control group (P<0.05) within 2h-24h after operation; serum cortisol level of patients in experimental group is obviously lower than that in control group (P<0.05) within 2h-24h after operation; TPVB onset time and range of spinal nerve block of patients in experimental group are obviously lower than that in control group (P<0.05), and the difference of time for fixing block level and postoperative recovery in experimental and control groups has no statistical significance (P>0.05). It can be concluded that TPVB combined dexmedetomidine with ropivacaine helps maintain stability of hemodynamics during operation and improve effect of postoperative analgesia. (C) 2018 Elsevier B.V. All rights reserved.