Association Of Humanin A Novel Mitochondrial Protein With Human Heart Failure: An Assessment Of Mortality And Clinical Biomarkers

Sati Patel,Jennifer D. Hwang, Hemalatha Narayanasamy,Luanda Grazette,Jeffrey Tran,Pinchas Cohen,Junxiang Wan

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY（2019）

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摘要

Mitochondrial dysfunction has been implicated in the early pathophysiology of heart failure (HF) of varied etiologies. Humanin (HN) is a novel mitochondrial peptide that promotes mitochondrial biogenesis and anti-apoptotic effects. Prior studies suggest that HN is cardioprotective by these

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humanin heart failure,mitochondrial protein,heart failure

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