Proteomic analyses of Urine Exosomes reveal New Biomarkers of Diabetes in Pregnancy
Journal of The American Academy of Dermatology(2016)
Abstract
Urinary exosome proteomic analysis non-invasively provides insights into maternal changes during diabetic pregnancy. Exosome biomarkers early in pregnancy can be potentially used to better understand pathophysiologic mechanisms of diabetes at a cellular level, and to distinguish between gestational and pre-gestational diabetes at the pathway level. This information can aid intervention efforts to improve pregnancy outcomes in women with diabetes.
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Key words
Damage associated molecular pattern,Diabetic pregnancy,Exosome,Gestational diabetes,Proteomics,S100A9,Urine exosomes
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