Computed Tomography-Guided Biopsy Assisted by 18F-FDG Coincidence Imaging for Solid Tumours

Objective: Early diagnosis of solid tumour is the key to making treatment plans. The traditional computed tomography (CT)-guided percutaneous biopsy often makes it difficult to determine the puncture point. The aim of this study is to analyze the collaborative application value of CT-guided biopsy assisted by F-18-FDG coincidence imaging for solid tumours. Methods: A retrospective analysis of 15 patients who underwent routine radiological examination can not form a correct diagnosis on body solid tumour. The needle was introduced under CT guidance in a step-by-step technique and correct needle position in the centre of FDG high concentration area in coincidence imaging. The biopsy specimens were examined under light microscopy and immunofluorescence. Result All the lesions were successfully punctured, and the final diagnosis was malignant in 14 cases and benign in 1 cases. The sensitivity of CT-guided biopsy assisted by coincidence imaging was 92.9% (13/14), and the specificity was 100% (1/1). Compared with clinical final diagnosis, there was no significant difference between the two groups (P > 0.05). Two cases of lung biopsy patients had a small amount of blood in sputum after operation. Conclusion: The CT-guided biopsy assisted by F-18-FDG coincidence imaging may improve the diagnostic capability, especially in cases when a definitive diagnosis by imaging alone is difficult to make.