Abstract 20906: Prognosis in Heart Failure: A TNM-Like Classification for Risk Stratification

Introduction: NYHA is the most used classification for heart failure (HF), but it does not include patient’s clinical features. We proposed a new staging system for HF, named HLM (JACC 2014;20;63(19):1959-60), analogous to the TNM classification used in Oncology. HLM refers to heart damage (H), lung involvement (L), and malfunction (M) of peripheral organs (i.e. kidney, liver, hematopoiesis and central nervous system). Hypothesis: The aim was a preliminary comparison between HLM and NYHA at 6 and 12 months to assess the most accurate prognosis of HF patients in terms of rehospitalization for major adverse cardiovascular and cerebrovascular events (MACCE) and mortality. Methods: We enrolled 1064 consecutive patients with the diagnosis of or at risk for HF. According to HLM classification, all parameters for heart, lungs and peripheral organs function were collected and each patient was classified according to NYHA and HLM. At 6 and 12 months patients were followed up for rehospitalization for MACCE and car...