Methanol extract of Cola nitida ameliorates inflammation and nociception in experimental animals

Lawrence Dayo Adedayo,Alaba Olumide Ojo,Funmileyi Olubanjo Awobajo,Boluwatife Adetoyin Adeboye, James Adedayo Adebisi, Temitope Joshua Bankole, Gideon Opeyemi Ayilara,Olubayode Bamidele,Nimedia Gideon Aitokhuehi,Samuel Adetunji Onasanwo

Neurobiology of Pain（2019）

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摘要

•Methanol extract Cola nitida possesses analgesic properties in mice.•Methanol extract of Cola nitida showed anti-inflammatory activity.•Methanol extract of cola nitida mediates its nociceptive action through cholinergic pathway.•Opioid and beta adrenergic pathways do not mediate the analgesic potential of Cola nitida.

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关键词

Analgesic,Anti-inflammation,Cola nitida,Carrageenan

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