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Incidence, Patterns, and Outcomes with Adjuvant Chemotherapy for Residual Disease After Neoadjuvant Chemotherapy in Muscle-invasive Urinary Tract Cancers

Nieves Martinez Chanza,Lillian Werner,Elizabeth Plimack,Evan Y. Yu,Ajjai S. Alva,Simon J. Crabb, Thomas Powles,Jonathan E. Rosenberg,Jack Baniel,Ulka N. Vaishampayan,Dominik R. Berthold,Sylvain Ladoire,Syed A. Hussain,Matthew I. Milowsky,Neeraj Agarwal,Andrea Necchi,Sumanta K. Pal,Cora N. Sternberg,Joaquim Bellmunt,Matthew D. Galsky,Lauren C. Harshman

European Urology Oncology（2020）

Cited 13|Views88
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Abstract
The utilization of adjuvant chemotherapy after neoadjuvant chemotherapy in patients with high-risk residual disease is not frequent but might reduce the risk of recurrence. Participation in the ongoing adjuvant immunotherapy trials and development of other prospective studies are warranted to resolve this question.
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Key words
Adjuvant chemotherapy,Muscle-invasive bladder cancer,Muscle-invasive urinary tract cancer,Neoadjuvant chemotherapy,Residual disease,Risk of relapse,Time to recurrence
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